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1
Sporotrichosis is an emerging mycosis caused by the Sporothrix schenckii complex and is increasingly reported worldwide, with the highest burden in South America and Asia.
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2
Disseminated sporotrichosis is uncommon and occurs more often in immunocompromised patients, but it can also occur without overt immunodeficiency and may resemble tuberculosis.
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3
A 78-year-old man with treated diffuse large B-cell lymphoma in long-term remission developed disseminated subcutaneous nodules and was empirically treated for tuberculosis because of granulomatous inflammation and local TB endemicity.
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4
Fungal culture identified Sporothrix schenckii complex, prompting treatment with amphotericin B followed by itraconazole; the cutaneous lesions healed and pulmonary abnormalities markedly improved.
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5
Diagnosis requires a high index of suspicion, especially in tuberculosis-endemic settings, because disseminated sporotrichosis can resemble tuberculosis and other infections associated with granulomatous inflammation.
