Impact of center volume on outcomes in allogeneic hematopoietic cell transplantation for children - Takeaways - MDSpire

Impact of center volume on outcomes in allogeneic hematopoietic cell transplantation for children

  • By

  • Motohiro Kato

  • Hideki Nakashone

  • Keitaro Matsuo

  • Yuri Ito

  • Atsumi Yanagisawa

  • Marie Ohbiki

  • Ken Tabuchi

  • Tatsuo Ichinohe

  • Yoshiko Hashii

  • Junya Kanda

  • Hideki Goto

  • Koji Kato

  • Makoto Yoshimitsu

  • Atsushi Sato

  • Moeko Hino

  • Kimikazu Matsumoto

  • Kimikazu Yakushijin

  • Yoshiko Atsuta

  • Takahiro Fukuda

  • April 10, 2025

  • 0 min

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  • 1

    Hematopoietic cell transplantation (HCT) is a curative option for various pediatric conditions, but it carries significant risks of complications.

  • 2

    Center volume may influence post-transplant outcomes, with high-volume centers potentially benefiting from greater experience in managing complications.

  • 3

    Pediatric transplantation differs from adult practices, necessitating specific studies to assess the center effect on outcomes in children.

  • 4

    The study analyzed data from 6966 pediatric patients across 123 centers, categorizing them by transplant volume over 20 years.

  • 5

    Overall 5-year survival rates showed no statistically significant differences among center categories, indicating similar outcomes across volumes.

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