Cognitive outcomes after endovascular thrombectomy in ischemic stroke: a systematic review

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Endovascular thrombectomy (EVT) improves cognitive outcomes in acute ischemic stroke compared to intravenous thrombolysis (IVT) or best medical therapy.
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Cognitive benefits from EVT are most pronounced in executive functions, with variable effects on memory and persistent cognitive deficits remaining common.
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Larger infarct volumes and longer reperfusion times are associated with worse cognitive outcomes following EVT.
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A systematic review of 23 studies highlighted the need for standardized cognitive assessments in future EVT research.
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Despite the advantages of EVT, post-stroke cognitive impairment affects over two-thirds of stroke survivors, impacting long-term independence.

Frontiers In Medicine

by Wiktoria Balcerzak, Gabriela Początek, Anetta Lasek-Bal, Agnieszka Gorzkowska
May 11, 2026

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