Impact of Thyroiditis on the Diagnostic Accuracy of Fine-Needle Aspiration Cytology: A Clinico-Radiological and Cytological Evaluation of Discordance Risk Factors - Takeaways - MDSpire

Impact of Thyroiditis on the Diagnostic Accuracy of Fine-Needle Aspiration Cytology: A Clinico-Radiological and Cytological Evaluation of Discordance Risk Factors

  • By

  • Matrix M. H. Fung

  • Anthony T. Y. Ng

  • Nicholas T. C. Ng

  • Joanna K. M. Ng

  • Joshua J. X. Li

  • Philippe Vielh

  • Philip P. C. Ip

  • February 25, 2026

  • 0 min

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  • 1

    Thyroiditis can induce atypical cytomorphological changes, impacting the diagnostic accuracy of fine-needle aspiration cytology.

  • 2

    The study analyzed 770 thyroid aspirates, revealing varying risks of neoplasm and malignancy between thyroiditis and non-thyroiditis groups.

  • 3

    In the thyroiditis group, the risk of neoplasm and malignancy was notably lower for certain Bethesda diagnostic categories.

  • 4

    Concordance rates for cytology-histology were slightly lower in the thyroiditis group, particularly when considering atypical cases.

  • 5

    Demographic and clinical factors, including type of thyroiditis, influenced the diagnostic outcomes but did not significantly alter concordance rates.

Original Source(s)

Impact of Thyroiditis on the Diagnostic Accuracy of Fine-Needle Aspiration Cytology: A Clinico-Radiological and Cytological Evaluation of Discordance Risk Factors

  • by Matrix M. H. Fung, Anthony T. Y. Ng, Nicholas T. C. Ng, Joanna K. M. Ng, Joshua J. X. Li, Philippe Vielh, Philip P. C. Ip

  • February 25, 2026

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