PD-1 inhibitor combined with chemoradiotherapy in two cases of ovarian cancer brain metastases: a case report - Takeaways - MDSpire

PD-1 inhibitor combined with chemoradiotherapy in two cases of ovarian cancer brain metastases: a case report

  • By

  • Yanke Li

  • Yu Xia

  • Lei Wang

  • Xiaomei Liu

  • Zhenhua Du

  • May 28, 2026

  • 0 min

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  • 1

    PD-1 inhibitors combined with chemotherapy and targeted therapy may improve outcomes in ovarian cancer patients with brain metastases.

  • 2

    A patient with a single brain metastasis achieved complete response and prolonged progression-free survival after comprehensive treatment.

  • 3

    The patient with multiple brain metastases showed short-term efficacy but ultimately died due to complications.

  • 4

    Higher expression of immune markers in brain metastases suggests enhanced immune activity compared to primary tumors.

  • 5

    Further research is needed to explore the correlation between immune markers and treatment response in brain metastases.

Original Source(s)

PD-1 inhibitor combined with chemoradiotherapy in two cases of ovarian cancer brain metastases: a case report

  • by Yanke Li, Yu Xia, Lei Wang, Xiaomei Liu, Zhenhua Du

  • May 28, 2026

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