Association of the serum uric acid to high-density lipoprotein cholesterol ratio with in-hospital mortality in patients with acute kidney injury: a retrospective cohort study - Takeaways - MDSpire

Association of the serum uric acid to high-density lipoprotein cholesterol ratio with in-hospital mortality in patients with acute kidney injury: a retrospective cohort study

  • By

  • Desheng Zhang

  • Gen Li

  • Guohao Xu

  • Lijun Yin

  • Jianghua Guo

  • Jun Lv

  • June 19, 2026

  • 0 min

Share

  • 1

    The study analyzed 500 adult patients with acute kidney injury (AKI) to evaluate the prognostic value of the uric acid to HDL cholesterol ratio (UHR).

  • 2

    Out of 500 patients, 435 survived while 65 did not, with non-survivors being older and having more severe renal impairment and inflammation.

  • 3

    Multivariate analyses indicated that each unit increase in UHR was associated with a 55% higher hazard of in-hospital mortality (HR: 1.55; p=0.002).

  • 4

    The association between UHR and mortality was stronger in older patients and those with higher serum creatinine and elevated C-reactive protein levels.

  • 5

    The findings support UHR as an independent predictor of in-hospital mortality in AKI, highlighting its potential for risk stratification.

Original Source(s)

Association of the serum uric acid to high-density lipoprotein cholesterol ratio with in-hospital mortality in patients with acute kidney injury: a retrospective cohort study

  • by Desheng Zhang, Gen Li, Guohao Xu, Lijun Yin, Jianghua Guo, Jun Lv

  • June 19, 2026

Related Content

Electrical Impedance Tomography in Nonintubated Patients: Advancing Validation and Defining Clinical Value

Real-time assessment of exercise rehabilitation and symptoms in hospitalized COPD patients

Case Report: Fabry disease mimicking coronary artery disease and hypertrophic cardiomyopathy—a 15-year diagnostic delay