Ovarian endometriosis associated with significantly elevated CA19-9: a case report - Takeaways - MDSpire

Significant Elevation of CA19-9 in a Case of Ovarian Endometriosis: A Clinical Report

  • By

  • Yue Hu

  • Jiali Ruan

  • Xuelian Du

  • July 21, 2026

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  • 1

    CA19-9 is a tumor marker primarily linked to pancreaticobiliary and gastrointestinal malignancies, with rare elevation in benign conditions like ovarian endometriosis.

  • 2

    A 44-year-old female presented with elevated CA19-9 levels (2453.1 U/mL) and symptoms including abdominal pain and weight loss, raising suspicion for malignancy.

  • 3

    Extensive evaluations, including MRI and endoscopy, ruled out gastrointestinal malignancies before confirming ovarian endometriosis through laparoscopy.

  • 4

    Postoperative endocrine therapy led to normalization of CA19-9 levels, with no recurrence of lesions observed during follow-up.

  • 5

    The case highlights the need for comprehensive evaluation in patients with elevated CA19-9 to differentiate between benign and malignant ovarian conditions.

Original Source(s)

Ovarian endometriosis associated with significantly elevated CA19-9: a case report

  • by Yue Hu, Jiali Ruan, Xuelian Du

  • July 21, 2026

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