Tumour volume as a predictor of postoperative speech impairment in children undergoing resection of posterior fossa tumours: a prospective, multicentre study - Takeaways - MDSpire

Tumour volume as a predictor of postoperative speech impairment in children undergoing resection of posterior fossa tumours: a prospective, multicentre study

  • By

  • Aske Foldbjerg Laustsen

  • Shivaram Avula

  • Jonathan Grønbæk

  • Barry Pizer

  • Per Nyman

  • Pelle Nilsson

  • Radek Frič

  • Magnus Aasved Hjort

  • Vladimír Beneš

  • Peter Hauser

  • Beatrix Pálmafy

  • Giedre Rutkauskiene

  • Florian Wilhelmy

  • Rick Brandsma

  • Astrid Sehested

  • René Mathiasen

  • Marianne Juhler

  • April 3, 2025

  • 0 min

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  • 1

    Cerebellar mutism syndrome (CMS) is a significant complication of posterior fossa tumour surgery, leading to postoperative speech impairment in 30% of cases.

  • 2

    Current research primarily focuses on age, tumour location, and pathology as risk factors for CMS, with limited exploration of tumour size.

  • 3

    This study aims to determine if larger posterior fossa tumour volumes correlate with a higher risk of postoperative speech impairment.

  • 4

    The study utilizes a semi-automated segmentation model for accurate tumour volume measurement, enhancing risk assessment and surgical planning.

  • 5

    Findings may improve understanding of CMS risk factors, potentially leading to better patient outcomes in managing paediatric posterior fossa tumours.

Original Source(s)

Tumour volume as a predictor of postoperative speech impairment in children undergoing resection of posterior fossa tumours: a prospective, multicentre study

  • by Aske Foldbjerg Laustsen, Shivaram Avula, Jonathan Grønbæk, Barry Pizer, Per Nyman, Pelle Nilsson, Radek Frič, Magnus Aasved Hjort, Vladimír Beneš, Peter Hauser, Beatrix Pálmafy, Giedre Rutkauskiene, Florian Wilhelmy, Rick Brandsma, Astrid Sehested, René Mathiasen, Marianne Juhler

  • April 3, 2025

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