Lactate Dehydrogenase-to-Albumin Ratio Predicts 30-Day and 90-Day Mortality in Glucocorticoid-Treated ICU Patients With Pneumonia: A Secondary Analysis of a Multicenter Cohort - Takeaways - MDSpire

Lactate Dehydrogenase-to-Albumin Ratio Predicts 30-Day and 90-Day Mortality in Glucocorticoid-Treated ICU Patients With Pneumonia: A Secondary Analysis of a Multicenter Cohort

  • By

  • Han, Dan dan

  • Sun, fa Sheng

  • Liu, Ai

  • Hao, Cuiping

  • Sun, ping Jian

  • April 16, 2026

  • 0 min

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  • 1

    The lactate dehydrogenase-to-albumin ratio (LAR) is a proposed biomarker for predicting mortality in pneumonia patients on glucocorticoids.

  • 2

    In a study of 499 ICU patients, a LAR cutoff of 13.39 was identified as optimal for predicting 30-day and 90-day mortality.

  • 3

    High LAR (≥13.39) was linked to significantly increased mortality rates: 45.8% at 30 days and 51.4% at 90 days.

  • 4

    LAR remained an independent mortality predictor after multivariable adjustment, with hazard ratios of 2.07 for 30 days and 1.93 for 90 days.

  • 5

    Incorporating LAR into clinical assessments may improve risk stratification and management for pneumonia patients receiving glucocorticoids.

Original Source(s)

Lactate Dehydrogenase-to-Albumin Ratio Predicts 30-Day and 90-Day Mortality in Glucocorticoid-Treated ICU Patients With Pneumonia: A Secondary Analysis of a Multicenter Cohort

  • by Han, Dan dan, Sun, fa Sheng, Liu, Ai , Hao, Cuiping , Sun, ping Jian

  • April 16, 2026

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