Role of psychological resilience and psychological distress in linking fear of disease progression to quality of life in chronic heart failure: a cross-sectional serial mediation analysis - Takeaways - MDSpire

Role of psychological resilience and psychological distress in linking fear of disease progression to quality of life in chronic heart failure: a cross-sectional serial mediation analysis

  • By

  • Hong Ding

  • Xiaoxia Fang

  • Shixun Li

  • Liyun Miao

  • Xiao Wu

  • May 25, 2026

  • 0 min

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  • 1

    The study involved 212 patients with chronic heart failure (CHF) to explore the relationship between fear of disease progression and quality of life.

  • 2

    Fear of disease progression (FoP) was found to negatively impact quality of life (QoL) in CHF patients, with a direct effect observed.

  • 3

    Psychological resilience and psychological distress were identified as significant serial mediators in the relationship between FoP and QoL.

  • 4

    Higher levels of psychological resilience correlated with lower psychological distress and improved QoL among patients with CHF.

  • 5

    Clinical interventions should focus on enhancing psychological resilience and reducing distress to improve QoL for CHF patients.

Original Source(s)

Role of psychological resilience and psychological distress in linking fear of disease progression to quality of life in chronic heart failure: a cross-sectional serial mediation analysis

  • by Hong Ding, Xiaoxia Fang, Shixun Li, Liyun Miao, Xiao Wu

  • May 25, 2026

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