Influence of Heart Function on the Assessment of MASLD Using Indocyanine Green Clearance

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Metabolic dysfunction-associated steatotic liver disease (MASLD) is a significant target for treatment in patients undergoing metabolic and bariatric surgery (MBS).
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Indocyanine green (ICG) clearance is a noninvasive method used to assess liver function, relying on hepatic blood flow and cellular uptake.
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This study hypothesized that ICG clearance is lower in MASLD patients compared to controls and correlates with histological severity assessed by liver biopsy.
4

Cardiac output (CO) was suggested to influence ICG clearance interpretation, potentially enhancing its diagnostic accuracy for MASLD.
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The study involved a controlled design with patients undergoing MBS and cholecystectomy, measuring ICG clearance and cardiac function parameters.

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