Passive leg raising and microvascular skin blood flow to predict peripheral tissue perfusion fluid responsiveness - Takeaways - MDSpire

Passive leg raising and microvascular skin blood flow to predict peripheral tissue perfusion fluid responsiveness

  • By

  • Alexandra Morin

  • Tomas Urbina

  • Juliette Bernier

  • Lisa Raia

  • Vincent Bonny

  • Louai Missri

  • Jean-Luc Baudel

  • Pierre-Yves Boelle

  • Eric Maury

  • Jérémie Joffre

  • Hafid Ait-Oufella

  • January 21, 2026

  • 0 min

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  • 1

    Sepsis is linked to peripheral tissue hypoperfusion, which correlates with poor outcomes and organ failure.

  • 2

    Fluid resuscitation is critical in sepsis management, but both under-resuscitation and fluid overload can increase mortality.

  • 3

    Passive leg raising (PLR) is a dynamic test that predicts cardiac output response to volume expansion without fluid administration.

  • 4

    Microvascular skin blood flow (SBF) monitoring provides real-time assessment of tissue perfusion and correlates with clinical markers.

  • 5

    This study evaluates the effectiveness of combining PLR with SBF monitoring to predict microvascular fluid responsiveness in septic patients.

Original Source(s)

Passive leg raising and microvascular skin blood flow to predict peripheral tissue perfusion fluid responsiveness

  • by Alexandra Morin, Tomas Urbina, Juliette Bernier, Lisa Raia, Vincent Bonny, Louai Missri, Jean-Luc Baudel, Pierre-Yves Boelle, Eric Maury, Jérémie Joffre, Hafid Ait-Oufella

  • January 21, 2026

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