Prognostic value of the TAPSE/PASP-ratio in patients with severe mitral regurgitation undergoing transcatheter edge-to-edge mitral valve repair - Takeaways - MDSpire

Prognostic value of the TAPSE/PASP-ratio in patients with severe mitral regurgitation undergoing transcatheter edge-to-edge mitral valve repair

  • By

  • Felix Ausbuettel

  • Fares Kano

  • Nikolaos Patsalis

  • Christin Fichera

  • Dimitar Divchev

  • Carlo-Federico Fichera

  • July 2, 2026

  • 0 min

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  • 1

    Mitral valve regurgitation is prevalent in patients over 75 years, with transcatheter edge-to-edge repair emerging as a viable treatment option.

  • 2

    Right ventricular dysfunction negatively impacts long-term survival, but quantifying it remains complex due to various influencing factors.

  • 3

    The TAPSE/D-PASP ratio is used to assess RV-PA coupling, with a ratio < 0.37 mm/mmHg indicating RV-PA uncoupling.

  • 4

    In a study of 158 patients undergoing M-TEER, RV-PA uncoupling was observed in 32.3% of cases.

  • 5

    The study followed patients for a median of 499 days, with a non-significant trend towards shorter follow-up in those with RV-PA uncoupling.

Original Source(s)

Prognostic value of the TAPSE/PASP-ratio in patients with severe mitral regurgitation undergoing transcatheter edge-to-edge mitral valve repair

  • by Felix Ausbuettel, Fares Kano, Nikolaos Patsalis, Christin Fichera, Dimitar Divchev, Carlo-Federico Fichera

  • July 2, 2026

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