Growth and Fibrosis in Children With Biliary Atresia: A Retrospective Cohort Study - Takeaways - MDSpire
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Child Growth and Fibrosis Associated with Biliary Atresia: Findings from a Retrospective Cohort Analysis

  • By

  • Cecilie Lindebjerg

  • Martin Bo Rasmussen

  • Lars Søndergaard Johansen

  • Thora Wesenberg Helt

  • Vibeke Brix Christensen

  • September 5, 2026

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  • 1

    Biliary atresia (BA) is a rare inflammatory disorder affecting bile ducts, with a prevalence of 1 in 14,000 to 20,000 births in Europe.

  • 2

    Without treatment, children with BA typically develop cirrhosis within 6 months and liver failure within 1 year.

  • 3

    The study examines growth patterns and catch-up growth in children with BA, considering the impact of liver transplantation and fibrosis severity.

  • 4

    Data were collected from electronic patient records, including anthropometric measurements and blood tests, over a period from 2006 to 2024.

  • 5

    Liver fibrosis was assessed using non-invasive measures like the AST-to-platelet ratio index (APRI) and the FIB-4 score.

Original Source(s)

Growth and Fibrosis in Children With Biliary Atresia: A Retrospective Cohort Study

  • by Cecilie Lindebjerg, Martin Bo Rasmussen, Lars Søndergaard Johansen, Thora Wesenberg Helt, Vibeke Brix Christensen

  • September 5, 2026

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