Survival without major morbidity in very preterm infants (<32 weeks’ gestation): prevalence, temporal trends, and associated factors in a single-center retrospective cohort - Takeaways - MDSpire
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Outcomes of Very Preterm Infants (<32 Weeks’ Gestation) Surviving Without Major Morbidity: A Single-Center Retrospective Study on Prevalence, Trends, and Contributing Factors

  • By

  • Liu Yang

  • Yikun Zhang

  • Chuan Nie

  • Zhiren Chen

  • Yumei Jian

  • Di Zhong

  • Yuanhan Qin

  • August 28, 2026

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  • 1

    The study analyzed 1,172 very preterm infants admitted to the NICU from January 2021 to October 2025 at Guangdong Women and Children Hospital.

  • 2

    Survival without major morbidity (SWMM) was achieved in 59.9% of the complete-care cohort, with survival rates remaining high and stable during the study period.

  • 3

    Increased gestational age and birth weight were associated with higher odds of SWMM, while male sex and lower Apgar scores correlated with lower odds.

  • 4

    The incidence of bronchopulmonary dysplasia and severe retinopathy of prematurity increased over time, despite stable survival rates.

  • 5

    Discharges against medical advice (DAMA) occurred in 6.7% of VPIs, decreasing significantly with increasing gestational age.

Original Source(s)

Survival without major morbidity in very preterm infants (<32 weeks’ gestation): prevalence, temporal trends, and associated factors in a single-center retrospective cohort

  • by Liu Yang, Yikun Zhang, Chuan Nie, Zhiren Chen, Yumei Jian, Di Zhong, Yuanhan Qin

  • August 28, 2026

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