Neurological complications of Orthopoxvirus infections: neurotropism and neurovirulence - Takeaways - MDSpire

Neurological complications of Orthopoxvirus infections: neurotropism and neurovirulence

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Monkeypox virus (MPXV) was declared a global health emergency by WHO in 2022 due to its neurological disease potential.
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MPXV infection can lead to neurological symptoms such as headaches, seizures, and encephalopathy, alongside typical poxvirus signs.
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MRI findings in MPXV-infected individuals may show brain edema, indicating central nervous system involvement.
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Orthopoxviruses, including MPXV, can cross the blood-brain barrier, raising concerns about their neurotropic properties.
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The review discusses the neuropathogenesis of orthopoxviruses and highlights diagnostic and therapeutic considerations.

Brain

Frontiers In Neurology

Frontiers In Neurology

Frontiers In Neurology

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