Case Report: A case of primary renal synovial sarcoma - Takeaways - MDSpire

Case Report: A case of primary renal synovial sarcoma

  • By

  • Xuan Li

  • Jiahao Su

  • Zijie Tang

  • Yuan Li

  • Xiaogang Feng

  • Feng Lin

  • Hanyu Chen

  • Qizhong Fu

  • Xujie Liu

  • Ying Liu

  • May 21, 2026

  • 0 min

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  • 1

    A 53-year-old male was diagnosed with primary renal synovial sarcoma after presenting with intermittent lumbar and abdominal pain.

  • 2

    Imaging revealed a large left renal mass measuring 13.3 cm × 11.6 cm, suggestive of malignancy.

  • 3

    Postoperative analysis confirmed synovial sarcoma through immunohistochemistry and identification of the SS18-SSX2 fusion gene.

  • 4

    The patient underwent four cycles of chemotherapy with epirubicin and ifosfamide, showing no signs of recurrence or metastasis.

  • 5

    Primary renal synovial sarcoma is rare, accounting for less than 2% of renal malignancies, and requires specific diagnostic approaches.

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