Effects of dexmedetomidine nasal spray on perioperative anxiety and quality of postoperative recovery in patients undergoing modified radical mastectomy for breast cancer - Takeaways - MDSpire

Effects of dexmedetomidine nasal spray on perioperative anxiety and quality of postoperative recovery in patients undergoing modified radical mastectomy for breast cancer

  • By

  • Qi Han

  • Zichao Li

  • Hongyi Xiao

  • Fanceng Ji

  • Chunhui Zheng

  • Qinglan Li

  • June 15, 2026

  • 0 min

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  • 1

    Preoperative intranasal dexmedetomidine significantly reduced perioperative anxiety in breast cancer patients undergoing modified radical mastectomy.

  • 2

    Patients receiving dexmedetomidine had higher Quality of Recovery-15 scores at 24 and 48 hours post-surgery compared to the control group.

  • 3

    No significant differences were found in intraoperative hemodynamics, anesthetic consumption, or vasoactive drug use between the two groups.

  • 4

    Time to emergence from anesthesia was significantly longer in the dexmedetomidine group compared to the control group.

  • 5

    The study was a randomized, double-blind trial involving 90 female patients scheduled for modified radical mastectomy.

Original Source(s)

Effects of dexmedetomidine nasal spray on perioperative anxiety and quality of postoperative recovery in patients undergoing modified radical mastectomy for breast cancer

  • by Qi Han, Zichao Li, Hongyi Xiao, Fanceng Ji, Chunhui Zheng, Qinglan Li

  • June 15, 2026

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