Do Revisions in Rotator Cuff Repair Decline With GLP-1 Use? - Takeaways - MDSpire

Do Revisions in Rotator Cuff Repair Decline With GLP-1 Use?

Preoperative use was associated with fewer revisions and no increase in short-term complications among patients with obesity, although benefits appeared concentrated in select subgroups.

  • By

  • Andrea Surnit

  • June 24, 2026

  • 4 min

Share

  • 1

    Preoperative use of GLP-1 receptor agonists may lower revision rates in patients with obesity undergoing arthroscopic rotator cuff repair.

  • 2

    The study matched 1,183 patients receiving GLP-1 receptor agonists with controls, revealing lower revision rates for left-sided repairs.

  • 3

    At 1 and 2 years, revision rates were 2% and 4% for GLP-1 users compared to 7% and 8% for controls.

  • 4

    No significant differences in retear rates were found overall, but lower rates were noted among females with left-sided repairs.

  • 5

    The study's limitations include reliance on administrative data and lack of detailed clinical information on surgical factors.

Original Source(s)

Do Revisions in Rotator Cuff Repair Decline With GLP-1 Use?

  • by Andrea Surnit

  • June 24, 2026

Related Content

Research landscape, hotspots, and evolutionary trends of knee osteoarthritis and oxidative stress: a multidimensional bibliometric analysis

CAA Use Tied to Higher Arthroplasty Risk

In a UK cohort, patients with osteoarthritis who initiated centrally acting analgesics had a higher hazard of knee or hip replacement than those who initiated SSRIs, though residual confounding by pain severity remains a key limitation.

PRP Linked to Better Outcomes in Advanced Knee OA

In a small open-label randomized trial, 2 platelet-rich plasma injections were associated with greater 6-month improvements in pain and function than corticosteroid injection or oral aceclofenac among patients awaiting knee arthroplasty.