Elevated triglyceride glucose-body mass index is associated with a higher risk of reduced cumulative live birth and adverse pregnancy outcomes in women undergoing assisted reproductive technology: a retrospective cohort study - Takeaways - MDSpire

Elevated triglyceride glucose-body mass index is associated with a higher risk of reduced cumulative live birth and adverse pregnancy outcomes in women undergoing assisted reproductive technology: a retrospective cohort study

  • By

  • Jie Hu

  • Shujuan Ma

  • Yinyan Gao

  • Yangqin Peng

  • Xiaojuan Wang

  • Irene X. Y. Wu

  • Fei Gong

  • June 17, 2026

  • 0 min

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  • 1

    The study included 53,393 women undergoing assisted reproductive technology between January 2017 and March 2023.

  • 2

    A significant inverse association was found between maternal TyG-BMI and cumulative live birth rates.

  • 3

    Women in the highest TyG-BMI tertile had a lower cumulative live birth rate compared to those in the lowest tertile.

  • 4

    Higher TyG-BMI was linked to increased risks of miscarriage, fetal loss, preterm birth, and macrosomia.

  • 5

    TyG-BMI may serve as a cost-effective marker for assessing insulin resistance and reproductive outcomes in ART.

Original Source(s)

Elevated triglyceride glucose-body mass index is associated with a higher risk of reduced cumulative live birth and adverse pregnancy outcomes in women undergoing assisted reproductive technology: a retrospective cohort study

  • by Jie Hu, Shujuan Ma, Yinyan Gao, Yangqin Peng, Xiaojuan Wang, Irene X. Y. Wu, Fei Gong

  • June 17, 2026

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