Atherogenic index of plasma and severe headaches or migraines risk in US adults: a population-based cross-sectional analysis from NHANES 1999–2004 - Takeaways - MDSpire

Atherogenic index of plasma and severe headaches or migraines risk in US adults: a population-based cross-sectional analysis from NHANES 1999–2004

  • By

  • Shaoxiong Chen

  • Yi He

  • Jiaheng Xu

  • May 26, 2026

  • 0 min

Share

  • 1

    The study analyzed NHANES data from 1999 to 2004 to explore the association between plasma atherogenic index (AIP) and severe headaches or migraines.

  • 2

    Higher risks of severe headaches or migraines were found in individuals with elevated AIP, particularly in the second and fourth quartiles.

  • 3

    Subgroup analyses indicated that younger adults, females, and those without diabetes or coronary heart disease had a higher risk of severe headaches or migraines.

  • 4

    The eXtreme Gradient Boosting modeling identified AIP as a significant feature associated with severe headaches or migraines.

  • 5

    While elevated AIP was linked to severe headaches or migraines, a consistent dose-response relationship was not established, necessitating further research.

Original Source(s)

Atherogenic index of plasma and severe headaches or migraines risk in US adults: a population-based cross-sectional analysis from NHANES 1999–2004

  • by Shaoxiong Chen, Yi He, Jiaheng Xu

  • May 26, 2026

Related Content

Assessment of an AI-Driven System for Systematic Diagnosis of Headache Disorders According to ICHD-3 Guidelines

MRI May Define Two Distinct Migraine Phenotypes

Patients with greater migraine burden showed widespread connectivity changes and lower cortical volume.

Zack Z. Ramilevich, M.D., Joins Marcus Neuroscience Institute as a General Neurologist

Board-certified neurologist Zack Z. Ramilevich, M.D., has joined Marcus Neuroscience Institute, part of Baptist Health, as a general neurologist.

  • by

  • March 26, 2026

  • 2 min