Non-linear and context-dependent association of maternal BMI with cumulative live birth in Chinese women undergoing intrauterine insemination: a retrospective study of 3788 cycles - Takeaways - MDSpire

Non-linear and context-dependent association of maternal BMI with cumulative live birth in Chinese women undergoing intrauterine insemination: a retrospective study of 3788 cycles

  • By

  • Zhou, Huan-Qun

  • Zhu, Jian-Fang

  • Wang, Ai-Ai

  • Yuan, Qi-Long

  • Wu, Aihua

  • Lu, Shan

  • Zhou, Wen

  • May 22, 2026

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  • 1

    Maternal BMI showed no significant association with clinical pregnancy or live birth in the first IUI cycle.

  • 2

    Per-cycle analysis indicated a modest positive correlation between maternal BMI and live birth rates.

  • 3

    Cumulative success rates demonstrated a non-linear pattern, peaking at a BMI of approximately 21.2 kg/m².

  • 4

    Subgroup analyses revealed heterogeneities in BMI associations based on basal FSH levels and treatment protocols.

  • 5

    The study highlights the need for individualized preconception management regarding maternal BMI and IUI success.

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