A systematic review and meta-analysis of the effects of exercise training on dysfunction in acute, subacute, and chronic stroke patients - Takeaways - MDSpire

A systematic review and meta-analysis of the effects of exercise training on dysfunction in acute, subacute, and chronic stroke patients

  • By

  • Jing Tan

  • Yongyan Tang

  • Daobin Han

  • May 14, 2026

  • 0 min

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  • 1

    This review evaluates the efficacy of exercise training in stroke patients during acute, subacute, and chronic phases.

  • 2

    The meta-analysis included 16 RCTs and 22 observational studies with 5,254 subjects, highlighting significant improvements in functional outcomes.

  • 3

    Exercise training initiated in the acute phase resulted in greater enhancements in Fugl-Meyer Assessment scores compared to subacute and chronic phases.

  • 4

    The acute stage exercise training group showed superior advancements in balance and mobility measures compared to the subacute stage group.

  • 5

    Caution is advised in interpreting results due to variability and the need for rigorous RCTs to determine optimal timing for exercise interventions.

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