Liver function estimation using multiphase hepatic CT: diagnostic performance of iodine-uptake and volumetric parameters - Takeaways - MDSpire

Liver function estimation using multiphase hepatic CT: diagnostic performance of iodine-uptake and volumetric parameters

  • By

  • Yasunori Nagayama

  • Masamichi Hokamura

  • Narumi Taguchi

  • Yasuhiro Yokota

  • Takumi Osaki

  • Koji Ogasawara

  • Shinya Shiraishi

  • Ryuya Yoshida

  • Ryota Harai

  • Masafumi Kidoh

  • Seitaro Oda

  • Takeshi Nakaura

  • Toshinori Hirai

  • March 13, 2025

  • 0 min

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  • 1

    Accurate liver function estimation is crucial for assessing chronic liver disease severity and planning surgeries to reduce liver failure risk.

  • 2

    ICG-R15 is a validated dynamic test for liver function, indicating severe dysfunction when ≥ 20%, and is recommended before hepatectomy.

  • 3

    99mTc-GSA scintigraphy evaluates regional hepatocyte function but has limitations such as high cost and limited availability.

  • 4

    Iodine-uptake parameters from multiphase hepatic CT may serve as potential markers for liver fibrosis and function assessment.

  • 5

    This study aims to correlate multiphase hepatic CT parameters with liver function measured by ICG-R15 and identify severe dysfunction.

Original Source(s)

Liver function estimation using multiphase hepatic CT: diagnostic performance of iodine-uptake and volumetric parameters

  • by Yasunori Nagayama, Masamichi Hokamura, Narumi Taguchi, Yasuhiro Yokota, Takumi Osaki, Koji Ogasawara, Shinya Shiraishi, Ryuya Yoshida, Ryota Harai, Masafumi Kidoh, Seitaro Oda, Takeshi Nakaura, Toshinori Hirai

  • March 13, 2025

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