MRI-based habitat radiomics for preoperative prediction of axillary pathological complete response in breast cancer after neoadjuvant therapy: a multicenter study - Takeaways - MDSpire

MRI-based habitat radiomics for preoperative prediction of axillary pathological complete response in breast cancer after neoadjuvant therapy: a multicenter study

  • By

  • Lei Ma

  • Shunian Li

  • Ziwei Cao

  • Jun Liao

  • Mengting Xu

  • Chuanjian Lv

  • Chunmiao Xu

  • Hongna Tan

  • May 13, 2026

  • 0 min

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  • 1

    A multicenter study developed an MRI-based habitat radiomics nomogram to predict axillary pathological complete response after neoadjuvant therapy in breast cancer.

  • 2

    The study included 336 women with node-positive breast cancer, utilizing dynamic contrast-enhanced MRI for tumor segmentation and habitat subregion definition.

  • 3

    The nomogram demonstrated the highest predictive performance with an AUC of 0.845 in the training cohort and maintained strong performance in validation cohorts.

  • 4

    Calibration analysis indicated good agreement between predicted and observed axillary pathological complete response, enhancing clinical decision-making.

  • 5

    The MRI-based habitat radiomics nomogram may assist in individualized axillary risk stratification, reducing the need for invasive surgical procedures.

Original Source(s)

MRI-based habitat radiomics for preoperative prediction of axillary pathological complete response in breast cancer after neoadjuvant therapy: a multicenter study

  • by Lei Ma, Shunian Li, Ziwei Cao, Jun Liao, Mengting Xu, Chuanjian Lv, Chunmiao Xu, Hongna Tan

  • May 13, 2026

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