Multimodal management of late-stage Bockenheimer disease complicated by severe anemia and coagulopathy: a case report - Takeaways - MDSpire

Multimodal management of late-stage Bockenheimer disease complicated by severe anemia and coagulopathy: a case report

  • By

  • Zilu Wang

  • Mingzhe Wen

  • Qianyun Han

  • Deming Wang

  • Lixin Su

  • Xindong Fan

  • April 30, 2026

  • 0 min

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  • 1

    Bockenheimer disease is a rare venous malformation affecting the upper extremity, causing pain, swelling, and hematologic complications.

  • 2

    A 14-year-old girl with late-stage Bockenheimer disease presented severe anemia and coagulopathy, requiring complex management.

  • 3

    The treatment involved anticoagulation, sclerotherapy, local suture ligation, and molecular targeted medication, leading to significant improvement.

  • 4

    Follow-up after 9 months showed recovery of anemia, well-controlled coagulopathy, and volume reduction in the affected limb.

  • 5

    Multimodal therapy is essential for managing Bockenheimer disease, emphasizing the importance of early intervention and monitoring hematologic profiles.

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