Does active surveillance prior to radical prostatectomy increase the risk of adverse pathological findings or postoperative prostate cancer treatment? - Takeaways - MDSpire

Does Preoperative Active Surveillance Elevate the Risk of Negative Pathological Outcomes or Subsequent Treatment for Prostate Cancer Following Radical Prostatectomy?

By
Ingrid Hannestad
Tor Åge Myklebust
Sophie D. Fosså
Stig Muller
Kirsti Aas
September 19, 2026

World Journal Of Urology

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1

Men with low- and favorable intermediate-risk prostate cancer often undergo active surveillance to avoid overtreatment.
2

Deferred radical prostatectomy after active surveillance may be associated with more adverse pathological findings compared to immediate surgery.
3

A Swedish study indicated that delayed radical prostatectomy increases the risk of salvage radiotherapy, but newer data showed no increase in post-surgery treatment.
4

The study utilized data from the Norwegian Prostate Cancer Registry, including men diagnosed between 2009 and 2022.
5

At diagnosis, men undergoing deferred radical prostatectomy had more favorable disease characteristics than those receiving immediate surgery.

Original Source(s)

World Journal Of Urology

Does active surveillance prior to radical prostatectomy increase the risk of adverse pathological findings or postoperative prostate cancer treatment?

by Ingrid Hannestad, Tor Åge Myklebust, Sophie D. Fosså, Stig Muller, Kirsti Aas
September 19, 2026

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