Ultrasound common hepatic artery denervation (CHA-D) as a novel neuromodulatory strategy for cardiovascular-kidney-metabolic syndrome: first-in-human experience - Takeaways - MDSpire

Ultrasound common hepatic artery denervation (CHA-D) as a novel neuromodulatory strategy for cardiovascular-kidney-metabolic syndrome: first-in-human experience

  • By

  • Mert Tokcan

  • Franciska Diana Wolter

  • Mathias Hohl

  • Peter Fries

  • Thorsten Kessler

  • Saarraaken Kulenthiran

  • Michael Böhm

  • June 3, 2026

  • 0 min

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  • 1

    Ultrasound-guided common hepatic artery denervation (CHA-D) is explored as a novel treatment for uncontrolled hypertension and cardiometabolic syndrome.

  • 2

    The procedure was performed on a patient with severe hypertension unresponsive to standard treatments, highlighting its potential as an alternative.

  • 3

    Pre-procedural assessments included imaging and laboratory tests to ensure patient safety and eligibility for CHA-D.

  • 4

    The intervention involved selective catheterization and ultrasound ablation of the common hepatic artery, monitored for safety throughout.

  • 5

    Initial findings suggest that CHA-D may enhance blood pressure reduction and improve metabolic parameters in patients with resistant hypertension.

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