Subtle Laboratory and Clinical Precursors of Celiac Disease in Young Adults: A Large-Scale Retrospective Cohort Study - Takeaways - MDSpire

Subtle Laboratory and Clinical Precursors of Celiac Disease in Young Adults: A Large-Scale Retrospective Cohort Study

  • By

  • Ramon Cohen

  • Shay Nemet

  • Alena Kirzhner

  • Tal Schiller

  • Haitham Abu Khadija

  • Shira Bezalel-Rosenberg

  • Ilan Asher

  • Ali Abdallah

  • Keren Mahlab-Guri

  • Daniel Elbirt

  • January 23, 2026

  • 0 min

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  • 1

    Celiac disease affects about 1% of the global population, with higher prevalence due to underdiagnosis and diagnostic delays.

  • 2

    Young adults often present with non-classical symptoms of celiac disease, leading to prolonged diagnostic delays and increased risk of complications.

  • 3

    Diagnostic delays for celiac disease are significantly longer in adults, averaging 90 months compared to 7.6 months in children.

  • 4

    This study aims to characterize pre-diagnostic symptoms and laboratory findings in young adults to improve early recognition of celiac disease.

  • 5

    The study uses a retrospective cohort design, analyzing data from Clalit Health Services to identify early predictors of celiac disease.

Original Source(s)

Subtle Laboratory and Clinical Precursors of Celiac Disease in Young Adults: A Large-Scale Retrospective Cohort Study

  • by Ramon Cohen, Shay Nemet, Alena Kirzhner, Tal Schiller, Haitham Abu Khadija, Shira Bezalel-Rosenberg, Ilan Asher, Ali Abdallah, Keren Mahlab-Guri, Daniel Elbirt

  • January 23, 2026

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