Efficacy and safety of intranasal dexmedetomidine vs. oral chloral hydrate sedation for transthoracic echocardiography in infants with congenital heart disease aged under 3 months: a retrospective study - Takeaways - MDSpire

Efficacy and safety of intranasal dexmedetomidine vs. oral chloral hydrate sedation for transthoracic echocardiography in infants with congenital heart disease aged under 3 months: a retrospective study

  • By

  • Jingjing Lv

  • Lihong Jin

  • June 25, 2026

  • 0 min

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  • 1

    This study compares intranasal dexmedetomidine and oral chloral hydrate for sedation in infants under 3 months with congenital heart disease.

  • 2

    A total of 383 infants were analyzed, showing higher initial sedation success rates with dexmedetomidine compared to chloral hydrate.

  • 3

    Sedation onset and discharge times were significantly shorter in the dexmedetomidine group than in the chloral hydrate group.

  • 4

    The decline in heart rate was greater in the dexmedetomidine group, but no severe adverse reactions were reported.

  • 5

    Low body weight and prolonged fasting time were identified as independent risk factors affecting sedation success rates.

Original Source(s)

Efficacy and safety of intranasal dexmedetomidine vs. oral chloral hydrate sedation for transthoracic echocardiography in infants with congenital heart disease aged under 3 months: a retrospective study

  • by Jingjing Lv, Lihong Jin

  • June 25, 2026

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