Long-term psychological and functional outcomes after hepatitis C eradication with direct-acting antivirals: an 80-month follow-up study - Takeaways - MDSpire

Long-term psychological and functional outcomes after hepatitis C eradication with direct-acting antivirals: an 80-month follow-up study

  • By

  • Salvatore Cipolla

  • Pierluigi Catapano

  • Maria Chiara Della Corte

  • Daniele De Francesco

  • Antonio Volpicelli

  • Iolanda Cafarella

  • Filomena Boccia

  • Lorenzo Bertolino

  • Emanuele Durante-Mangoni

  • Rosa Zampino

  • Mario Luciano

  • May 25, 2026

  • 0 min

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  • 1

    Eighty months post-DAA treatment, patients with a psychiatric history showed significant improvements in depressive and anxiety symptoms.

  • 2

    Patients without prior psychiatric issues maintained stable psychological profiles, reflecting earlier improvements in mood and anxiety.

  • 3

    Both patient groups experienced a decline in physical quality of life, indicating a need for ongoing support post-treatment.

  • 4

    Avoidant coping strategies and psychiatric history negatively predicted long-term changes in anxiety levels after treatment.

  • 5

    The study highlights the sustained psychiatric safety of DAAs, emphasizing the importance of integrated medical and psychological follow-up.

Original Source(s)

Long-term psychological and functional outcomes after hepatitis C eradication with direct-acting antivirals: an 80-month follow-up study

  • by Salvatore Cipolla, Pierluigi Catapano, Maria Chiara Della Corte, Daniele De Francesco, Antonio Volpicelli, Iolanda Cafarella, Filomena Boccia, Lorenzo Bertolino, Emanuele Durante-Mangoni, Rosa Zampino, Mario Luciano

  • May 25, 2026

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