Late gadolinium enhancement CMR for detecting myocardial injury after cancer therapy: a real-world observational study

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Late gadolinium enhancement (LGE) cardiac MRI effectively identifies myocardial damage in cancer patients undergoing treatment.
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Patients with LGE exhibited significantly reduced left ventricular ejection fraction (LVEF) and peak strain compared to LGE-negative patients.
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Moderate to strong correlations were found between myocardial strain metrics and LVEF in cancer patients, indicating strain's relevance in assessing cardiac function.
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Multivariate analysis revealed significant relationships between cardiac biomarkers and myocardial strain, highlighting their potential in monitoring cardiotoxicity.
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LGE presence is a critical risk factor for left ventricular dysfunction in cancer survivors, emphasizing the need for careful cardiac monitoring.

Frontiers In Cardiovascular Medicine

by Xi Liu, Yue Gao, Zhen Wang, Wei-Feng Yan, Rui Shi, Yuan Li, Ying-Shi Sun, Zhi-Gang Yang
May 1, 2026

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