Clinical characteristics and long-term prognosis of talaromycosis in children with novel and reported inborn errors of immunity - Takeaways - MDSpire

Clinical characteristics and long-term prognosis of talaromycosis in children with novel and reported inborn errors of immunity

  • By

  • Qian Lu

  • Xianghui Li

  • Zhiwen Jiang

  • Tiantian Li

  • Bingkun Li

  • Lan Huang

  • Qihua Huang

  • Dongmei Hu

  • Chunying Lv

  • Guoqun Liu

  • Jialing Zhong

  • Jingjing Lin

  • Liuwei Liao

  • Qianfeng Qin

  • Sha Qin

  • Haotian Shao

  • Zhiyi Wang

  • Xiuying Li

  • Li Jiang

  • Xinyu Zhang

  • Lili Wei

  • Jiarong Liang

  • Dongyan Zheng

  • Shuangjie Wang

  • Weixuan Wu

  • Kaisu Pan

  • Yanqing Zheng

  • Yanning Li

  • Qing Tang

  • Min Jiang

  • Wanqing Liao

  • Cunwei Cao

  • May 13, 2026

  • 0 min

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  • 1

    The study analyzed 18 pediatric patients with talaromycosis and inborn errors of immunity over a 13-year period.

  • 2

    All children diagnosed with talaromycosis had inborn errors of immunity, including both novel and known genetic anomalies.

  • 3

    Half of the children experienced severe complications, necessitating advanced life support, with a median antifungal therapy duration of 16 months.

  • 4

    Despite challenges, four children achieved long-term relapse-free survival, while six remained stable on maintenance antifungal therapy.

  • 5

    Talaromycosis may indicate underlying inborn errors of immunity in children, highlighting the need for prolonged antifungal and immunostimulatory therapy.

Original Source(s)

Clinical characteristics and long-term prognosis of talaromycosis in children with novel and reported inborn errors of immunity

  • by Qian Lu, Xianghui Li, Zhiwen Jiang, Tiantian Li, Bingkun Li, Lan Huang, Qihua Huang, Dongmei Hu, Chunying Lv, Guoqun Liu, Jialing Zhong, Jingjing Lin, Liuwei Liao, Qianfeng Qin, Sha Qin, Haotian Shao, Zhiyi Wang, Xiuying Li, Li Jiang, Xinyu Zhang, Lili Wei, Jiarong Liang, Dongyan Zheng, Shuangjie Wang, Weixuan Wu, Kaisu Pan, Yanqing Zheng, Yanning Li, Qing Tang, Min Jiang, Wanqing Liao, Cunwei Cao

  • May 13, 2026

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