Integrating multimodal prehabilitation into enhanced recovery after surgery programs (MPhERAS) for elderly patients: a systematic review and meta-analysis of randomized controlled trials and cohort studies - Takeaways - MDSpire

Integrating multimodal prehabilitation into enhanced recovery after surgery programs (MPhERAS) for elderly patients: a systematic review and meta-analysis of randomized controlled trials and cohort studies

  • By

  • A. Srinivasan

  • K. M. Yi

  • D. Sharma

  • S. K. Mantoo

  • December 27, 2025

  • 0 min

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  • 1

    The study evaluates the effectiveness of multimodal prehabilitation within ERAS for elderly patients undergoing elective colorectal surgery.

  • 2

    Six studies with low risk of bias included 547 patients, focusing on outcomes like length of stay, 6-min walk test, complications, and quality of life.

  • 3

    A statistically significant improvement was observed in the 6-min walk test, with a mean difference of 18.38 m (p = 0.0404).

  • 4

    No significant differences were found for length of stay, postoperative complications, or quality of life in the study.

  • 5

    The findings suggest potential for multimodal prehabilitation in ERAS, but further research is needed to strengthen evidence in specific patient populations.

Original Source(s)

Integrating multimodal prehabilitation into enhanced recovery after surgery programs (MPhERAS) for elderly patients: a systematic review and meta-analysis of randomized controlled trials and cohort studies

  • by A. Srinivasan, K. M. Yi, D. Sharma, S. K. Mantoo

  • December 27, 2025

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