A family and healthcare-associated cluster of severe fever with thrombocytopenia syndrome in Shanghai, China: an epidemiological investigation in a nonendemic area - Takeaways - MDSpire
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Investigation of a Family and Healthcare-Related Outbreak of Severe Fever with Thrombocytopenia Syndrome in Shanghai, China: An Epidemiological Study in a Non-Endemic Region

  • By

  • Yiyi Zhu

  • Wencheng Wu

  • Zheng Teng

  • Yaxu Zheng

  • Yuanping Wang

  • Wei Wang

  • Jian Chen

  • Hao Pan

  • September 14, 2026

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  • 1

    Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV) and has a reported case-fatality rate of 6% to 30%.

  • 2

    First identified in China in 2011, SFTS has since been reported elsewhere in Asia, while its reported incidence in China has shown a fluctuating upward trend.

  • 3

    SFTSV is transmitted primarily through tick bites but can also spread between people through close contact with infected blood or bloody secretions.

  • 4

    The cluster involved seven symptomatic individuals—five family members and two healthcare workers—with clinical manifestations of varying severity.

  • 5

    Investigators followed China’s 2010 SFTS guidelines, documenting clinical and exposure histories and testing specimens for SFTSV RNA and specific antibodies.

Original Source(s)

A family and healthcare-associated cluster of severe fever with thrombocytopenia syndrome in Shanghai, China: an epidemiological investigation in a nonendemic area

  • by Yiyi Zhu, Wencheng Wu, Zheng Teng, Yaxu Zheng, Yuanping Wang, Wei Wang, Jian Chen, Hao Pan

  • September 14, 2026

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