Occult cervical microinvasive squamous cell carcinoma with superficial endometrial spread mimicking high-grade squamous intraepithelial lesion in a postmenopausal woman: a case report - Takeaways - MDSpire

Occult cervical microinvasive squamous cell carcinoma with superficial endometrial spread mimicking high-grade squamous intraepithelial lesion in a postmenopausal woman: a case report

  • By

  • Yuying Chen

  • Xi Zhao

  • Gege Wang

  • Ziwei Liu

  • Guangchao Sun

  • Yan Jia

  • July 16, 2026

Share

  • 1

    A 56-year-old postmenopausal woman was misdiagnosed with high-grade squamous intraepithelial lesion during conization.

  • 2

    Final pathology revealed microinvasive squamous cell carcinoma with superficial endometrial spread, not identified in initial assessments.

  • 3

    Immunohistochemistry confirmed the cervical origin of the neoplasm, distinguishing it from primary endometrial disease.

  • 4

    Cervical atrophy in postmenopausal women may compromise diagnostic accuracy of colposcopy and conization.

  • 5

    The case emphasizes the need for careful evaluation of cervical lesions in postmenopausal women to avoid underestimating invasive disease.

Original Source(s)

Occult cervical microinvasive squamous cell carcinoma with superficial endometrial spread mimicking high-grade squamous intraepithelial lesion in a postmenopausal woman: a case report

  • by Yuying Chen, Xi Zhao, Gege Wang, Ziwei Liu, Guangchao Sun, Yan Jia

  • July 16, 2026

Related Content

Tissue-Resident NK Cells Slow Solid Tumor Growth in Mice

The study points to a possible off-the-shelf cell therapy for solid tumors

  • June 16, 2026

  • 3 min
Primary cutaneous adenoid cystic carcinoma of the right forearm: a case report and dermoscopic features

Chemical components of tattoo inks and their potential role in carcinogenesis and their side effects