Sequential immune-related nephritis and pneumonitis during immune checkpoint inhibitor therapy: a case report - Takeaways - MDSpire

Sequential immune-related nephritis and pneumonitis during immune checkpoint inhibitor therapy: a case report

  • By

  • Haocheng Zhao

  • Shanshan Lin

  • Lingzhi Wu

  • Wenqiu Wu

  • May 13, 2026

  • 0 min

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  • 1

    Immune checkpoint inhibitors can cause severe immune-related adverse events affecting multiple organs, including nephritis and pneumonitis.

  • 2

    The presented case involves a patient who developed immune-related nephritis followed by pneumonitis during corticosteroid tapering after initial recovery.

  • 3

    High-dose corticosteroids effectively treated the patient's acute kidney injury, leading to rapid recovery of kidney function.

  • 4

    As the steroid dose was reduced, the patient experienced new respiratory symptoms, indicating the emergence of immune-related pneumonitis.

  • 5

    This case underscores the need for close monitoring and timely adjustments in therapy to manage complex immune-related adverse events.

Original Source(s)

Sequential immune-related nephritis and pneumonitis during immune checkpoint inhibitor therapy: a case report

  • by Haocheng Zhao, Shanshan Lin, Lingzhi Wu, Wenqiu Wu

  • May 13, 2026

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