Multidisciplinary management promoting wound healing in a patient with Proteus syndrome: a case report - Takeaways - MDSpire

Multidisciplinary management promoting wound healing in a patient with Proteus syndrome: a case report

  • By

  • Yue Tan

  • Xu Zhang

  • Hai-Bin Wang

  • Li Wang

  • Wen-Shuang Qiu

  • June 15, 2026

  • 0 min

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  • 1

    Proteus syndrome is a rare genetic disorder caused by AKT1 mutations, leading to asymmetric overgrowth and severe complications.

  • 2

    A 14-year-old patient with Proteus syndrome developed a severe soft tissue infection due to lower limb deformity, complicating his treatment.

  • 3

    Individualized anti-infective interventions by a clinical pharmacist significantly improved the patient's treatment course and wound healing.

  • 4

    The case highlights the need for a coordinated healthcare approach to manage the diverse clinical presentations and complications of Proteus syndrome.

  • 5

    Current treatment options for Proteus syndrome focus on symptom management, as there are no targeted drug therapies available.

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