Assessment of Potential Drug–Drug Interactions and Associated Factors Among Pulmonary Inpatients in a Tertiary Care Hospital: A Cross-Sectional Study - Takeaways - MDSpire
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Evaluation of Possible Drug–Drug Interactions and Contributing Factors in Pulmonary Inpatients at a Tertiary Care Facility: A Cross-Sectional Analysis

  • By

  • Nim Bahadur Dangi

  • Hari Prasad Sapkota

  • Gobinda Kandel

  • Krishna Prasad Sapkota

  • June 25, 2026

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  • 1

    37.4% of pulmonary inpatients experienced at least one potential drug-drug interaction (pDDI) during hospitalization.

  • 2

    Significant predictors of pDDIs included polypharmacy, prolonged hospital stay, co-morbidities, alcohol use, and advanced age.

  • 3

    Lexicomp identified more pDDIs than Micromedex, although both databases showed moderate agreement in their findings.

  • 4

    The study was conducted in a tertiary care hospital in Chitwan, Nepal, focusing on hospitalized patients with pulmonary diseases.

  • 5

    Computerized drug interaction databases are essential for detecting pDDIs, but their cost can be a barrier in resource-limited settings.

Original Source(s)

Assessment of Potential Drug–Drug Interactions and Associated Factors Among Pulmonary Inpatients in a Tertiary Care Hospital: A Cross-Sectional Study

  • by Nim Bahadur Dangi, Hari Prasad Sapkota, Gobinda Kandel, Krishna Prasad Sapkota

  • June 25, 2026

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