Association between obstructive sleep apnea syndrome and blood pressure variability: a meta-analysis - Takeaways - MDSpire
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Linking Obstructive Sleep Apnea Syndrome to Variability in Blood Pressure: A Meta-Analytic Review

  • By

  • Huijia Lei

  • Bo Kong

  • Yanwei Lv

  • Xiaozhu Ge

  • July 6, 2026

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  • 1

    Obstructive sleep apnea syndrome (OSAS) is linked to increased cardiovascular risk and is prevalent in 9–38% of adults.

  • 2

    This meta-analysis included 11 studies with 1,261 OSAS patients and 826 controls, assessing blood pressure variability (BPV) via ambulatory monitoring.

  • 3

    OSAS was associated with significantly higher BPV across all periods, with the largest differences observed during nighttime.

  • 4

    Subgroup analyses indicated a trend of increasing BPV with greater OSAS severity, particularly for nighttime diastolic BP variability.

  • 5

    The certainty of evidence regarding the association between OSAS and BPV ranged from low to very low, highlighting substantial heterogeneity.

Original Source(s)

Association between obstructive sleep apnea syndrome and blood pressure variability: a meta-analysis

  • by Huijia Lei, Bo Kong, Yanwei Lv, Xiaozhu Ge

  • July 6, 2026

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