Timing of parathyroidectomy in kidney transplant candidates: a systematic review and a proposed clinical algorithm - Takeaways - MDSpire

Timing of parathyroidectomy in kidney transplant candidates: a systematic review and a proposed clinical algorithm

  • By

  • Yushuai Zhang

  • Lihong Song

  • Xuehai Bian

  • Yishen Zhao

  • Yutang Miao

  • July 3, 2026

  • 0 min

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  • 1

    Parathyroidectomy (PTx) is used for severe secondary hyperparathyroidism in kidney transplant candidates, but optimal timing remains controversial.

  • 2

    Eight observational studies involving 4355 patients were included in the systematic review comparing pre-transplant and post-transplant PTx.

  • 3

    Pre-transplant PTx may be associated with lower graft loss, but higher short-term morbidity compared to post-transplant PTx.

  • 4

    No long-term differences in renal function were observed between pre-transplant and post-transplant PTx groups.

  • 5

    A risk-stratified algorithm is proposed to guide PTx timing based on individual patient factors like waitlist time and PTH level.

Original Source(s)

Timing of parathyroidectomy in kidney transplant candidates: a systematic review and a proposed clinical algorithm

  • by Yushuai Zhang, Lihong Song, Xuehai Bian, Yishen Zhao, Yutang Miao

  • July 3, 2026

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