Assessment of Systemic Inflammatory Markers Linked to High-Density Lipoprotein Levels in Patients with Keratoconus: A Retrospective Case-Control Analysis - Takeaways - MDSpire

Assessment of Systemic Inflammatory Markers Linked to High-Density Lipoprotein Levels in Patients with Keratoconus: A Retrospective Case-Control Analysis

  • By

  • Burçin Çakır

  • Muhammed Muaz Osmanoğlu

  • Büşra Güner Sönmezoğlu

  • December 23, 2025

  • 0 min

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  • 1

    Keratoconus is a progressive ectatic condition characterized by conical protrusion of a thinned central cornea.

  • 2

    The study evaluated systemic inflammatory markers in keratoconus patients, focusing on MHR, NHR, LHR, NLR, and PHR.

  • 3

    Significant differences in PHR were found between keratoconus patients and healthy controls, indicating its potential as a biomarker.

  • 4

    No significant correlations were observed between corneal topography indices, BCVA, and systemic inflammatory markers.

  • 5

    The optimal PHR cutoff value for keratoconus was determined to be 4807, with 74.8% sensitivity and 45.5% specificity.

Original Source(s)

Assessment of Systemic Inflammatory Markers Linked to High-Density Lipoprotein Levels in Patients with Keratoconus: A Retrospective Case-Control Analysis

  • by Burçin Çakır, Muhammed Muaz Osmanoğlu, Büşra Güner Sönmezoğlu

  • December 23, 2025

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