Response quality of large language models on periprosthetic fractures: A comparative evaluation of ChatGPT, Gemini, and Claude - Takeaways - MDSpire
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Evaluating the Quality of Responses from Large Language Models on Periprosthetic Fractures: A Comparison of ChatGPT, Gemini, and Claude

  • By

  • Buğra Can

  • Anıl Agar

  • İrfan Arslan

  • September 29, 2026

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  • 1

    Large language models (LLMs) like ChatGPT, Gemini, and Claude are increasingly used for health information, especially regarding periprosthetic fractures.

  • 2

    Periprosthetic femoral fractures after total hip arthroplasty are significant complications linked to high morbidity, mortality, and healthcare costs.

  • 3

    A study compared responses from ChatGPT, Gemini, and Claude to standardized questions about periprosthetic fractures, focusing on accuracy and quality.

  • 4

    The evaluation involved a set of 25 questions addressing key patient concerns related to periprosthetic fractures, assessed by an expert panel.

  • 5

    The study aimed to provide insights into the safety, readability, and quality of LLM-generated responses for high-risk clinical inquiries.

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