Clinical Features, Microbial Profiles, and Antimicrobial Resistance in Neonates with Bloodstream Infections Due to ESKAPEEc Pathogens in Southwest China - Takeaways - MDSpire
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Clinical Features, Microbial Profiles, and Antimicrobial Resistance in Neonates with Bloodstream Infections Due to ESKAPEEc Pathogens in Southwest China

  • By

  • Xiaoshan Peng

  • Biao Chen

  • Chunmei Jing

  • Hong Wei

  • Hongmei Xu

  • Ruiqiu Zhao

  • December 23, 2025

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  • 1

    Neonatal bloodstream infections (BSIs) have a high morbidity and mortality rate, with case fatality rates reaching up to 19%.

  • 2

    ESKAPEEc pathogens contribute to 58.6%-76.3% of BSIs and are associated with increased healthcare costs and mortality.

  • 3

    A retrospective study analyzed 625 neonates with confirmed BSIs, revealing a 55.4% prevalence of ESKAPEEc infections.

  • 4

    The study highlighted the urgent need for early diagnosis and appropriate antimicrobial treatment to improve neonatal BSI outcomes.

  • 5

    Antimicrobial resistance among ESKAPEEc pathogens limits treatment options, necessitating regional analysis of microbial profiles.

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