Influence of PSA level at salvage radiotherapy on metastasis-free survival following radical prostatectomy

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Adjuvant radiotherapy (aRT) is recommended for high-risk patients post-radical prostatectomy to reduce recurrence risk.
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Salvage radiotherapy (sRT) significantly improves metastasis-free survival compared to observation after biochemical recurrence.
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Early initiation of sRT at a PSA level < 0.25 ng/ml may enhance cancer control outcomes in high-risk patients.
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The study analyzed 190 patients, focusing on the impact of PSA levels at sRT initiation on metastasis-free survival.
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Statistical analyses included Cox regression models to adjust for confounding factors affecting oncological outcomes.

World Journal Of Urology

by Mike Wenzel, Benedikt Lauer, Kathrin Burdenski, Nikolaos Tselis, Claus Rödel, Christian Brandts, Marit Ahrens, Jens Köllermann, Markus Graefen, Clara Humke, Carolin Siech, Benedikt Hoeh, Felix K. H. Chun, Philipp Mandel
November 21, 2025

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