Urine Bladder Cancer Test Could Triage Cystoscopy

Real-world UK study suggests molecular testing could help prioritize patients with hematuria for urgent bladder investigation

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A urine-based DNA test can identify patients with hematuria who need urgent cystoscopy, allowing lower-risk patients to delay the procedure.
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The GALEAS Bladder assay detected 71 of 77 bladder cancers and had a negative predictive value exceeding 99 percent.
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The study involved 964 participants, with 77 confirmed cases of bladder cancer, highlighting the assay's diagnostic capabilities.
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Using the urine test could reduce immediate cystoscopies by 730 per 1000 patients without compromising overall clinical benefit.
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The study indicates a potential role for molecular testing as a triage tool, but randomized evidence is needed for broader recommendations.

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