BMI-specific nonlinear associations and threshold effects of the atherogenic index of plasma on incident prediabetes: insights from 100473 Chinese adults - Takeaways - MDSpire

BMI-specific nonlinear associations and threshold effects of the atherogenic index of plasma on incident prediabetes: insights from 100473 Chinese adults

  • By

  • Bing Wang

  • Weiqin Shen

  • Baoyin Li

  • Yesheng Pan

  • May 14, 2026

  • 0 min

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  • 1

    The study analyzed data from 100,473 Chinese adults to explore the relationship between plasma atherogenic index (AIP) and prediabetes.

  • 2

    A significant interaction between AIP and body mass index (BMI) was found, indicating that BMI modifies the association with prediabetes risk.

  • 3

    Nonlinear associations between AIP and prediabetes risk were observed only in normal-weight and overweight participants, not in underweight or obese individuals.

  • 4

    Inflection points for AIP were identified at -0.20 for normal-weight and 0.057 for overweight individuals, indicating threshold effects.

  • 5

    The findings suggest that AIP is a relevant marker for prediabetes risk, particularly in specific BMI categories among Chinese adults.

Original Source(s)

BMI-specific nonlinear associations and threshold effects of the atherogenic index of plasma on incident prediabetes: insights from 100473 Chinese adults

  • by Bing Wang, Weiqin Shen, Baoyin Li, Yesheng Pan

  • May 14, 2026

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