Efficacy and safety of continuous veno-venous hemofiltration for acute respiratory distress syndrome: a meta-analysis - Takeaways - MDSpire

Assessment of Continuous Veno-Venous Hemofiltration's Safety and Effectiveness in Acute Respiratory Distress Syndrome: A Meta-Analytic Review

  • By

  • Rui Wang

  • Sicheng Xu

  • July 17, 2026

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  • 1

    This meta-analysis evaluated the efficacy and safety of continuous veno-venous hemofiltration (CVVH) in patients with acute respiratory distress syndrome (ARDS).

  • 2

    The analysis included 28 randomized controlled trials with 1,739 ARDS patients, comparing CVVH outcomes to conventional treatment.

  • 3

    CVVH significantly improved oxygenation, reduced mortality, and shortened ICU and mechanical ventilation durations compared to conventional treatment.

  • 4

    No significant differences were found between CVVH and conventional treatment regarding PaCO₂ or cardiac index.

  • 5

    The study highlights the need for large-scale, multicenter RCTs to confirm CVVH's clinical value and optimize treatment protocols for ARDS.

Original Source(s)

Efficacy and safety of continuous veno-venous hemofiltration for acute respiratory distress syndrome: a meta-analysis

  • by Rui Wang, Sicheng Xu

  • July 17, 2026

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