The association between C-reactive protein-triglyceride glucose index and all-cause mortality in patients with cardiovascular-kidney-metabolic syndrome: a single-center retrospective cohort study - Takeaways - MDSpire

The association between C-reactive protein-triglyceride glucose index and all-cause mortality in patients with cardiovascular-kidney-metabolic syndrome: a single-center retrospective cohort study

  • By

  • Jiacai Lin

  • Shaobin Qiu

  • Shuling Su

  • Weixin Ni

  • Yongluan Lin

  • Xiaobin Ni

  • July 8, 2026

  • 0 min

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  • 1

    The study analyzed 8,632 patients with cardiovascular-kidney-metabolic syndrome to assess the prognostic value of the C-reactive protein-triglyceride glucose index.

  • 2

    CTI was found to be an independent predictor of all-cause mortality in both early (stage 0-3) and advanced (stage 4) CKM patients.

  • 3

    Patients in the highest quartile of CTI had a significantly increased mortality risk compared to those in the lowest quartile.

  • 4

    A linear dose-response relationship was confirmed between CTI levels and mortality risk across CKM stages.

  • 5

    CTI demonstrated superior predictive performance for 1-year mortality compared to the triglyceride-glucose index in CKM patients.

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