Risk-score performance for detecting transthyretin cardiac amyloidosis in severe aortic stenosis: a prospective cohort study - Takeaways - MDSpire

Risk-score performance for detecting transthyretin cardiac amyloidosis in severe aortic stenosis: a prospective cohort study

  • By

  • Graczyk Katarzyna

  • Dziewięcka Ewa

  • Winiarczyk Mateusz

  • Stępień Agnieszka

  • Przytuła Natalia

  • Holcman Katarzyna

  • Wiśniowska-Śmiałek Sylwia

  • Szot Wojciech

  • Kostkiewicz Magdalena

  • Rubiś Paweł

  • May 22, 2026

  • 0 min

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  • 1

    The study evaluated 104 patients with severe aortic stenosis to assess the prevalence of concomitant transthyretin cardiac amyloidosis.

  • 2

    Eighteen percent of patients with severe aortic stenosis were found to have transthyretin cardiac amyloidosis, indicating a significant coexistence.

  • 3

    Patients with both conditions were older and exhibited more arrhythmic disorders and lower left ventricular ejection fractions.

  • 4

    The eRAISE model demonstrated the highest diagnostic accuracy for identifying transthyretin cardiac amyloidosis in this cohort.

  • 5

    Implementing risk scores could enhance the detection of transthyretin cardiac amyloidosis in patients with severe aortic stenosis.

Original Source(s)

Risk-score performance for detecting transthyretin cardiac amyloidosis in severe aortic stenosis: a prospective cohort study

  • by Graczyk Katarzyna, Dziewięcka Ewa, Winiarczyk Mateusz, Stępień Agnieszka, Przytuła Natalia, Holcman Katarzyna, Wiśniowska-Śmiałek Sylwia, Szot Wojciech, Kostkiewicz Magdalena, Rubiś Paweł

  • May 22, 2026

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